SCHEMBL8539804

SCHEMBL8539804

CN(c1ccncc1)n1ccc2cc(O)ccc21

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 9/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7610158 0.82 SLC6A2 (1.00) SLC6A2
SCHEMBL9673016 0.80 SLC6A2 (0.46) SLC6A2
SCHEMBL8441967 0.80 SLC6A2 (0.73) SLC6A2
SCHEMBL7615812 0.78 SLC6A2 (1.00) SLC6A2
SCHEMBL7611251 0.77 SLC6A2 (0.62) SLC6A2
Fumaric Acid SCHEMBL7612128 0.76 SLC6A2 (0.79) SLC6A2
Maleic Acid SCHEMBL7612124 0.76 SLC6A2 (0.79) SLC6A2
SCHEMBL8539582 0.75 SLC6A2 (0.57) SLC6A2
SCHEMBL8541743 0.75 SLC6A2 (0.56) SLC6A2
Hydrochloric Acid SCHEMBL8544931 0.74 SLC6A2 (0.56) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0468401-B1 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments HOECHST MARION ROUSSEL INC (US) 1998-09-16 EP disclosed
US-5102891-A Useful for treating various memory dysfunctions such as alzheimer's disease HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1992-04-07 US disclosed
EP-0468401-A2 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1992-01-29 EP disclosed