Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718127 | 0.99 | GSK3B (0.47) | GSK3BTSHRADKCA1CA2 | |
| SCHEMBL4286250 | 0.99 | GSK3B (0.47) | GSK3BTSHRADKCA1CA2 | |
| SCHEMBL3363495 | 0.99 | GSK3B (0.47) | GSK3BTSHRADKCA1CA2 | |
| SCHEMBL6889028 | 0.99 | GSK3B (0.47) | GSK3BTSHRADKCA1CA2 | |
| SCHEMBL5697577 | 0.99 | GSK3B (0.47) | GSK3BTSHRADKCA1CA2 | |
| SCHEMBL11198199 | 0.99 | GSK3B (0.47) | GSK3BTSHRADKCA1CA2 | |
| SCHEMBL6882003 | 0.88 | GSK3B (0.38) | GSK3BTSHRADKCA1CA2 | |
| SCHEMBL15019404 | 0.86 | GSK3B (0.48) | GSK3BTSHRADKCA1CA2 | |
| SCHEMBL454030 | 0.86 | GSK3B (0.48) | GSK3BTSHRADKCA1CA2 | |
| SCHEMBL2161457 | 0.86 | GSK3B (0.48) | GSK3BTSHRADKCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851866-A1 | THERAPEUTIC COMPOUNDS | Oxford GlycoSciences (UK) Limited (GB) | 1998-07-08 | — | — | EP | claimed |
| WO-1997000882-A1 | THERAPEUTIC COMPOUNDS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 1997-01-09 | — | — | WO | claimed |