Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220669 | 1.00 | TACR1 (0.65) | TACR1 | |
| SCHEMBL9165193 | 0.91 | TACR1 (0.79) | TACR1 | |
| SCHEMBL9165199 | 0.91 | TACR1 (0.79) | TACR1 | |
| SCHEMBL9076634 | 0.91 | TACR1 (0.79) | TACR1 | |
| SCHEMBL8888434 | 0.85 | TACR1 (0.70) | TACR1 | |
| SCHEMBL31401699 | 0.84 | TACR1 (0.68) | TACR1 | |
| SCHEMBL9025510 | 0.83 | TACR1 (0.66) | TACR1 | |
| SCHEMBL9025495 | 0.83 | TACR1 (0.66) | TACR1 | |
| SCHEMBL9025492 | 0.83 | TACR1 (0.66) | TACR1 | |
| SCHEMBL9025141 | 0.82 | TACR1 (0.65) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683767-B1 | AZACYCLIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME (GB) | 1998-06-03 | — | — | EP | disclosed |
| WO-1994019323-A1 | AZACYCLIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1994-09-01 | — | — | WO | disclosed |