Acetic Acid

Acetic Acid

SCHEMBL8540401

CC(=O)O.CC(=O)O.CC(=O)O.NCC(N)Cc1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.60
PKM P14618 1/20 0.60
PTGS1 P23219 1/20 0.60
XIAP P98170 1/20 0.60
SLC7A5 Q01650 1/20 0.60
EPHX1 P07099 1/20 0.59
MMP2 P08253 3/20 0.56
ANPEP P15144 1/20 0.52
SLC15A1 P46059 1/20 0.51
SLC6A2 P23975 2/20 0.50
TAAR1 Q96RJ0 2/20 0.50
MAOA P21397 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
CYP2A6 P11509 1/20 0.50
ADORA2A P29274 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27733279 1.00 ALPI (0.60) ALPIPKMPTGS1XIAPSLC7A5
Carbamic Acid SCHEMBL28308217 0.90 EPHX1 (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL3441656 0.88 EPHX1 (0.76) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL243771 0.88 EPHX1 (0.76) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL137074 0.88 EPHX1 (0.76) ALPIPKMPTGS1XIAPSLC7A5
Phenylalanine Amide SCHEMBL10902583 0.87 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Phenylalanine Amide SCHEMBL10902576 0.87 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL18547947 0.86 EPHX1 (0.73) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL5567986 0.86 EPHX1 (0.73) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL9583547 0.86 EPHX1 (0.73) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820763-A2 Use of N,N'-dibenzyl-ethylene diamine acid derivatives as depigmentation agents L'OREAL (FR) 1998-01-28 EP disclosed
US-4770979-A Developer composition KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-09-13 US disclosed