Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829738 | 0.84 | AOC3 (0.53) | AOC3GAAALDH1A1MAPTHTR1A | |
| SCHEMBL28446300 | 0.84 | AOC3 (0.53) | AOC3GAAALDH1A1MAPTHTR1A | |
| SCHEMBL10327515 | 0.84 | AOC3 (0.53) | AOC3GAAALDH1A1MAPTHTR1A | |
| SCHEMBL19391564 | 0.84 | AOC3 (0.53) | AOC3GAAALDH1A1MAPTHTR1A | |
| SCHEMBL6478106 | 0.84 | AOC3 (0.53) | AOC3GAAALDH1A1MAPTHTR1A | |
| SCHEMBL7810785 | 0.82 | CYP19A1 (0.45) | ALDH1A1MAPTGSK3BMEN1CYP2D6 | |
| SCHEMBL31287488 | 0.82 | AOC3 (0.54) | AOC3GAAALDH1A1MAPTHTR1A | |
| SCHEMBL9085141 | 0.80 | AOC3 (0.56) | AOC3GAAALDH1A1MAPTHTR1A | |
| SCHEMBL6055130 | 0.80 | AOC3 (0.56) | AOC3GAAALDH1A1MAPTHTR1A | |
| SCHEMBL22034393 | 0.80 | AOC3 (0.49) | AOC3GAAALDH1A1MAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |