Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | ME2 | P23368 | 1/20 | 0.53 |
| ▸ | ME1 | P48163 | 1/20 | 0.53 |
| ▸ | ME3 | Q16798 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289171 | 0.84 | POLB (0.77) | POLBNPC1TDP1FKBP1AHPGD | |
| SCHEMBL4704100 | 0.83 | POLB (0.75) | POLBNPC1TDP1FKBP1AHPGD | |
| SCHEMBL24043594 | 0.82 | POLB (0.69) | POLBNPC1TDP1FKBP1AHPGD | |
| SCHEMBL7131839 | 0.82 | NPC1 (0.86) | POLBNPC1TDP1FKBP1AHPGD | |
| SCHEMBL1221986 | 0.82 | POLB (1.00) | POLBNPC1TDP1FKBP1AHPGD | |
| SCHEMBL4704483 | 0.82 | POLB (0.73) | POLBNPC1TDP1FKBP1AHPGD | |
| SCHEMBL14028152 | 0.82 | POLB (0.73) | POLBNPC1TDP1FKBP1AHPGD | |
| Hydrochloric Acid SCHEMBL27513272 | 0.81 | POLB (0.71) | POLBNPC1TDP1FKBP1AHPGD | |
| SCHEMBL18435561 | 0.81 | POLB (0.71) | POLBNPC1TDP1FKBP1AGRIN2B | |
| SCHEMBL8540623 | 0.81 | POLB (0.71) | POLBNPC1TDP1FKBP1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |