Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.58 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541660 | 0.90 | GRIN2B (0.59) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8542333 | 0.84 | GRIN2B (0.73) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8544678 | 0.82 | GRIN2B (0.55) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8546786 | 0.81 | GRIN2B (0.49) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8872091 | 0.80 | GRIN2B (0.67) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8542871 | 0.80 | GRIN2B (0.54) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8543112 | 0.79 | CARM1 (0.46) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8544330 | 0.79 | CARM1 (0.46) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8873054 | 0.77 | GRIN2B (0.46) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8546472 | 0.76 | GRIN1 (0.60) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |