Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439313 | 0.92 | MAOB (0.46) | HTR2CMAOBS1PR5CXCR2HRH1 | |
| SCHEMBL7100010 | 0.87 | HTR2C (0.43) | HTR2CMAOBS1PR5CXCR2HRH1 | |
| Hydrochloric Acid SCHEMBL1742023 | 0.86 | HTR2C (0.44) | HTR2CMAOBS1PR5CXCR2HRH1 | |
| SCHEMBL7453648 | 0.86 | HTR2C (0.40) | HTR2CMAOBS1PR5CXCR2HRH1 | |
| SCHEMBL7435086 | 0.85 | HTR2C (0.49) | HTR2CMAOBS1PR5CXCR2HRH1 | |
| SCHEMBL8542783 | 0.83 | MAOB (0.42) | HTR2CMAOBS1PR5HRH1HRH4 | |
| SCHEMBL8024707 | 0.83 | HTR2C (0.41) | HTR2CMAOBS1PR5HRH1HRH4 | |
| SCHEMBL6885675 | 0.83 | MAOB (0.41) | HTR2CMAOBS1PR5HRH1HRH4 | |
| SCHEMBL7454616 | 0.83 | HTR2C (0.41) | HTR2CMAOBS1PR5HRH1HRH4 | |
| SCHEMBL8541203 | 0.82 | HTR2C (0.42) | HTR2CMAOBHRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837848-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001536-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1997-01-16 | — | — | WO | disclosed |