Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283863 | 1.00 | POLA1 (0.69) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL23648123 | 1.00 | POLA1 (0.69) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL15720909 | 1.00 | POLA1 (0.69) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL8537214 | 0.92 | POLA1 (0.69) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL8539812 | 0.92 | POLA1 (0.69) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL3748702 | 0.91 | POLA1 (0.72) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL3748707 | 0.91 | POLA1 (0.72) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL25512701 | 0.91 | POLA1 (0.72) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL8541032 | 0.90 | POLA1 (0.68) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL5982591 | 0.90 | POLA1 (0.68) | POLA1KDM4EPNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |