Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429657 | 1.00 | CSNK1A1 (0.47) | CSNK1A1TYRO3DYRK1BNISCHTAAR1 | |
| SCHEMBL31429673 | 0.82 | CSNK1A1 (0.50) | CSNK1A1TYRO3DYRK1BNISCHALDH1A1 | |
| SCHEMBL9668125 | 0.82 | CSNK1A1 (0.50) | CSNK1A1TYRO3DYRK1BNISCHALDH1A1 | |
| SCHEMBL2011486 | 0.82 | NISCH (0.47) | CSNK1A1TYRO3DYRK1BNISCHTAAR1 | |
| SCHEMBL14886293 | 0.82 | CSNK1A1 (0.54) | CSNK1A1TYRO3DYRK1BNISCHTAAR1 | |
| SCHEMBL29483242 | 0.82 | NISCH (0.47) | CSNK1A1TYRO3DYRK1BNISCHTAAR1 | |
| SCHEMBL674011 | 0.82 | NISCH (0.53) | CSNK1A1TYRO3DYRK1BNISCHTAAR1 | |
| SCHEMBL11847005 | 0.79 | NISCH (0.44) | CSNK1A1TYRO3DYRK1BNISCHTAAR1 | |
| SCHEMBL4388545 | 0.79 | CSNK1A1 (0.47) | CSNK1A1TYRO3DYRK1BNISCHTAAR1 | |
| SCHEMBL1074245 | 0.79 | CSNK1A1 (0.47) | CSNK1A1TYRO3DYRK1BNISCHTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |