Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 5/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540099 | 1.00 | PTAFR (0.40) | PTAFRGBA1CES2CES1ALDH1A1 | |
| SCHEMBL8544017 | 1.00 | PTAFR (0.40) | PTAFRGBA1CES2CES1ALDH1A1 | |
| SCHEMBL8755757 | 1.00 | PTAFR (0.40) | PTAFRGBA1CES2CES1ALDH1A1 | |
| SCHEMBL9270382 | 1.00 | PTAFR (0.40) | PTAFRGBA1CES2CES1ALDH1A1 | |
| SCHEMBL9402754 | 1.00 | PTAFR (0.40) | PTAFRGBA1CES2CES1ALDH1A1 | |
| SCHEMBL8541049 | 1.00 | PTAFR (0.40) | PTAFRGBA1CES2CES1ALDH1A1 | |
| SCHEMBL8540008 | 0.94 | PTAFR (0.34) | PTAFRGBA1 | |
| SCHEMBL8537995 | 0.94 | PTAFR (0.34) | PTAFRGBA1 | |
| SCHEMBL8755760 | 0.94 | PTAFR (0.34) | PTAFRGBA1 | |
| SCHEMBL8541033 | 0.94 | PTAFR (0.34) | PTAFRGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594861-B1 | OPTICALLY ACTIVE TETRAHYDROPYRAN DERIVATIVE, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT BOTH CONTAINING THE SAME | KASHIMA OIL (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5443755-A | Optically active tetrahydropyrane derivatives, liquid crystal composition and liquid crystal device containing the same | KASHIMA OIL COMPANY (JP) | 1995-08-22 | — | — | US | disclosed |
| US-5368771-A | Enantiomorphs | KASHIMA OIL COMPANY (JP) | 1994-11-29 | — | — | US | disclosed |
| EP-0594861-A1 | OPTICALLY ACTIVE TETRAHYDROPYRAN DERIVATIVE, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT BOTH CONTAINING THE SAME | KASHIMA OIL COMPANY (JP) | 1994-05-04 | — | — | EP | disclosed |