Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 8/20 | 0.72 |
| ▸ | EGFR | P00533 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | APP | P05067 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | GALR3 | O60755 | 2/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | CCNC | P24863 | 2/20 | 0.50 |
| ▸ | CDK8 | P49336 | 2/20 | 0.50 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15684945 | 0.93 | HTT (0.63) | HTTEGFRLMNAAPPMAPK1 | |
| SCHEMBL9387280 | 0.85 | HTT (0.66) | HTTEGFRLMNAAPPMAPK1 | |
| SCHEMBL15684901 | 0.85 | EGFR (0.53) | HTTEGFRLMNAAPPMAPK1 | |
| SCHEMBL15684803 | 0.85 | HTT (0.56) | HTTEGFRLMNAAPPMAPK1 | |
| SCHEMBL8497590 | 0.84 | APP (1.00) | HTTEGFRLMNAAPPMAPK1 | |
| SCHEMBL9921377 | 0.84 | HTT (0.74) | HTTEGFRLMNAAPPMAPK1 | |
| SCHEMBL17803673 | 0.83 | HTT (0.81) | HTTEGFRLMNAAPPMAPK1 | |
| SCHEMBL23202914 | 0.82 | HTT (0.78) | HTTEGFRLMNAAPPMAPK1 | |
| SCHEMBL30827884 | 0.82 | HTT (0.78) | HTTEGFRLMNAAPPMAPK1 | |
| SCHEMBL8543175 | 0.82 | HTT (0.83) | HTTEGFRLMNAAPPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | claimed |
| CN-1052379-C | Quinazoline derisatives | DOWELANCO (US) | 2000-05-17 | — | — | CN | disclosed |
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | disclosed |
| CN-1035825-A | Quinazoline derivant | LILLY CO ELI (US) | 1989-09-27 | — | — | CN | disclosed |
| EP-0326329-A2 | Quinazoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |