SCHEMBL8541503

SCHEMBL8541503

c1ccc(CSCSCc2ccccc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.52
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
IDO1 P14902 3/20 0.46
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
NOS2 P35228 1/20 0.46
MAOB P27338 1/20 0.46
CALM1 P0DP23 1/20 0.45
POLB P06746 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14483860 0.97 CYP2C19 (0.50) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL206 0.88 CYP2C19 (0.56) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
Bromide SCHEMBL27685571 0.85 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5209412 0.85 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL27426987 0.85 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL27941071 0.85 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL27597743 0.85 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL7136112 0.85 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5209418 0.85 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
Ammonia Solution, Strong SCHEMBL27626378 0.85 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110713448-B Preparation method of carbon dioxide-participated dithioacetal 清华大学 2020-08-18 CN disclosed
CN-110713448-A Preparation method of carbon dioxide-participated dithioacetal 清华大学 2020-01-21 CN disclosed
EP-2116302-B1 Catalyst complex with a heterocyclic carbene ligand UNIV OF NEW ORLEANS FOUND (US) 2017-02-22 EP disclosed
EP-0884311-A2 Triazole Derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1998-12-16 EP disclosed