Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 18/20 | 0.44 |
| ▸ | NQO1 | P15559 | 6/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546725 | 0.91 | NQO1 (0.43) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL8545422 | 0.88 | NQO2 (0.42) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL9024039 | 0.87 | NQO2 (0.43) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL8541245 | 0.85 | NQO2 (0.40) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL8543086 | 0.85 | NQO2 (0.56) | NQO2NQO1MITF | |
| SCHEMBL8546029 | 0.83 | NQO2 (0.44) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL9023791 | 0.83 | NQO2 (0.45) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL8546284 | 0.79 | NQO2 (0.39) | NQO2NQO1 | |
| SCHEMBL9024175 | 0.79 | NQO2 (0.40) | NQO2NQO1SMARCA2 | |
| SCHEMBL8547450 | 0.79 | NQO1 (0.43) | NQO2NQO1MITFSMARCA2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487097-B1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5220026-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0487097-A1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |