Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 11/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546029 | 0.89 | NQO2 (0.44) | NQO2SMARCA2NQO1MITFKEAP1 | |
| SCHEMBL8546191 | 0.84 | IDO1 (0.37) | NQO2IDO1NQO1MITF | |
| SCHEMBL8546683 | 0.83 | NQO2 (0.52) | NQO2SMARCA2NSD2TOP2ATOP2B | |
| SCHEMBL8543978 | 0.81 | IDO1 (0.35) | NQO2NSD2IDO1TOP2APIM1 | |
| SCHEMBL8546725 | 0.81 | NQO1 (0.43) | NQO2SMARCA2NQO1MITFKEAP1 | |
| SCHEMBL8547904 | 0.80 | IDO1 (0.33) | NQO2IDO1NQO1MITF | |
| SCHEMBL8545091 | 0.80 | IDO1 (0.34) | NQO2IDO1NQO1 | |
| SCHEMBL9023832 | 0.79 | NQO2 (0.46) | NQO2SMARCA2NQO1MITFKEAP1 | |
| SCHEMBL9036810 | 0.79 | NQO2 (0.36) | NQO2SMARCA2NSD2IDO1NQO1 | |
| SCHEMBL8548375 | 0.78 | NQO2 (0.40) | NQO2SMARCA2NSD2NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487097-B1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5220026-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0487097-A1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |