Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 3/20 | 0.34 |
| ▸ | NQO2 | P16083 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545091 | 0.94 | IDO1 (0.34) | IDO1NQO1NQO2 | |
| SCHEMBL8547506 | 0.91 | NQO2 (0.36) | IDO1NQO1NQO2 | |
| SCHEMBL8541618 | 0.89 | MEN1 (0.39) | NQO1NQO2 | |
| SCHEMBL29369288 | 0.87 | IDO1 (0.37) | IDO1NQO1NQO2 | |
| SCHEMBL105984 | 0.87 | IDO1 (0.37) | IDO1NQO1NQO2 | |
| Hydrochloric Acid SCHEMBL1650422 | 0.85 | NQO2 (0.36) | IDO1NQO1NQO2 | |
| SCHEMBL8540653 | 0.85 | NQO2 (0.37) | IDO1NQO1NQO2 | |
| SCHEMBL8543506 | 0.84 | NQO1 (0.35) | NQO1NQO2 | |
| SCHEMBL8546191 | 0.83 | IDO1 (0.37) | IDO1NQO1NQO2 | |
| SCHEMBL8543978 | 0.81 | IDO1 (0.35) | IDO1NQO1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487097-B1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5220026-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0487097-A1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |