Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544094 | 1.00 | TACR1 (0.87) | TACR1 | |
| SCHEMBL8544092 | 1.00 | TACR1 (0.87) | TACR1 | |
| Hydrochloric Acid SCHEMBL8537523 | 0.99 | TACR1 (0.87) | TACR1 | |
| Hydrochloric Acid SCHEMBL8537528 | 0.99 | TACR1 (0.87) | TACR1 | |
| Hydrochloric Acid SCHEMBL8537521 | 0.99 | TACR1 (0.87) | TACR1 | |
| SCHEMBL2490482 | 0.94 | TACR1 (0.87) | TACR1 | |
| Hydrochloric Acid SCHEMBL8546033 | 0.93 | TACR1 (0.87) | TACR1 | |
| Vofopitant SCHEMBL310338 | 0.93 | TACR1 (1.00) | TACR1 | |
| Vofopitant SCHEMBL8431760 | 0.93 | TACR1 (1.00) | TACR1 | |
| Vofopitant SCHEMBL2996010 | 0.93 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720609-B1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LTD (GB) | 1998-11-11 | — | — | EP | disclosed |
| EP-0720609-A1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LIMITED (GB) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008549-A1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LIMITED (GB) | 1995-03-30 | — | — | WO | disclosed |