Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.30 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620112 | 0.87 | POLB (0.35) | POLBALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL8620116 | 0.87 | POLB (0.35) | POLBALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL8544565 | 0.84 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8544568 | 0.84 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL14985141 | 0.81 | POLB (0.37) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL17171857 | 0.81 | POLB (0.37) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8549371 | 0.79 | CYP3A4 (0.31) | POLB | |
| SCHEMBL8549375 | 0.79 | CYP3A4 (0.31) | POLB | |
| SCHEMBL8548898 | 0.76 | POLB (0.34) | POLBSMN1; SMN2RAB9A | |
| SCHEMBL8548894 | 0.76 | POLB (0.34) | POLBSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818455-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-01-14 | — | — | EP | disclosed |