Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.45 |
| ▸ | VEGFA | P15692 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581919 | 0.91 | AR (0.46) | AREPAS1VEGFAERBB2SLC22A12 | |
| SCHEMBL923176 | 0.90 | ERBB2 (0.53) | ARCYP19A1EPAS1ERBB2HTR2A | |
| SCHEMBL875648 | 0.87 | AR (0.47) | ARCYP19A1EPAS1VEGFA | |
| SCHEMBL26609303 | 0.81 | AR (0.45) | ARCYP19A1ERBB2SLC22A12HTR2A | |
| SCHEMBL922800 | 0.81 | EPAS1 (0.47) | ARCYP19A1EPAS1VEGFAERBB2 | |
| SCHEMBL8546460 | 0.80 | MAPT (0.42) | ARCYP19A1EPAS1VEGFAALDH1A1 | |
| SCHEMBL8616842 | 0.80 | AR (0.48) | ARERBB2CYP11B1CYP11B2TBXA2R | |
| SCHEMBL28671160 | 0.80 | AR (0.48) | ARERBB2ALDH1A1SMN1; SMN2SLC22A12 | |
| SCHEMBL29851244 | 0.80 | AR (0.48) | ARERBB2CYP11B1CYP11B2TBXA2R | |
| SCHEMBL29255047 | 0.80 | AR (0.48) | ARCYP19A1ALDH1A1SMN1; SMN2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |