Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539610 | 0.79 | SLC6A2 (0.56) | SLC6A2 | |
| SCHEMBL8539731 | 0.76 | SLC6A2 (0.57) | SLC6A2 | |
| SCHEMBL8544590 | 0.76 | SLC6A2 (0.65) | SLC6A2 | |
| SCHEMBL8543271 | 0.74 | SLC6A2 (0.66) | SLC6A2 | |
| SCHEMBL8539219 | 0.74 | SLC6A2 (0.65) | SLC6A2 | |
| SCHEMBL8441967 | 0.73 | SLC6A2 (0.73) | SLC6A2 | |
| SCHEMBL9738763 | 0.73 | SLC6A2 (0.61) | SLC6A2 | |
| SCHEMBL8544943 | 0.72 | SLC6A2 (0.62) | SLC6A2 | |
| Hydrochloric Acid SCHEMBL8544479 | 0.72 | SLC6A2 (0.60) | SLC6A2 | |
| SCHEMBL9672902 | 0.71 | SLC6A2 (0.62) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |