Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | STAT3 | P40763 | 3/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326753 | 0.89 | POLB (0.54) | MAPTALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL7335988 | 0.86 | MAPT (0.63) | MAPTALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL8547767 | 0.85 | MAPT (0.56) | MAPTALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL8542772 | 0.85 | F2 (0.68) | MAPTPOLBKDM4EGAALMNA | |
| SCHEMBL8540573 | 0.84 | POLB (0.52) | MAPTALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL8548405 | 0.83 | MAPT (0.56) | MAPTALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL7334623 | 0.83 | MAPT (0.56) | MAPTALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL7327021 | 0.83 | POLB (0.56) | MAPTALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL8542767 | 0.83 | F2 (0.74) | F2 | |
| SCHEMBL8542671 | 0.82 | MAPT (0.54) | MAPTALDH1A1HPGDPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |