Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL854548 | 0.82 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL3699875 | 0.81 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL853960 | 0.81 | NPSR1 (0.51) | TLR7TLR8 | |
| SCHEMBL3701040 | 0.75 | TLR7 (0.63) | TLR7 | |
| SCHEMBL6119291 | 0.73 | TLR7 (0.72) | TLR7TLR8 | |
| SCHEMBL8887148 | 0.73 | TLR7 (0.72) | TLR7TLR8 | |
| SCHEMBL6118784 | 0.73 | TLR7 (0.80) | TLR7TLR8 | |
| SCHEMBL6118752 | 0.73 | TLR7 (0.80) | TLR7TLR8 | |
| SCHEMBL8527802 | 0.70 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL8894288 | 0.70 | TLR7 (0.65) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432768-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | AstraZeneca AB (SE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133885-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | WO | disclosed |