Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545366 | 0.85 | FABP7 (0.36) | FABP7FABP5TP53TSHRCYP19A1 | |
| SCHEMBL7807916 | 0.85 | POLB (0.51) | POLBFABP7FABP5TP53CYP3A4 | |
| SCHEMBL10390625 | 0.85 | POLB (0.51) | POLBFABP7FABP5TP53CYP3A4 | |
| SCHEMBL9205704 | 0.82 | GAA (0.48) | POLBALDH1A1HPGD | |
| SCHEMBL9199841 | 0.82 | GAA (0.48) | POLBALDH1A1HPGD | |
| SCHEMBL9728346 | 0.82 | GAA (0.48) | POLBALDH1A1HPGD | |
| SCHEMBL9727869 | 0.82 | GAA (0.48) | POLBALDH1A1HPGD | |
| SCHEMBL9728425 | 0.82 | GAA (0.48) | POLBALDH1A1HPGD | |
| SCHEMBL9727808 | 0.82 | GAA (0.48) | POLBALDH1A1HPGD | |
| SCHEMBL7806845 | 0.81 | POLB (0.52) | POLBFABP7FABP5TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584085-B1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5554606-A | THIENAMYCIN DERIVATIVES; PSEUDOMONAS | ZENECA LIMITED (GB) | 1996-09-10 | — | — | US | disclosed |
| EP-0584085-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992017479-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD. (GB) | 1992-10-15 | — | — | WO | disclosed |