Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 8/20 | 0.38 |
| ▸ | NQO1 | P15559 | 4/20 | 0.38 |
| ▸ | TOP2A | P11388 | 5/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544353 | 0.95 | NQO2 (0.38) | NQO2NQO1TOP2AIDO1MEN1 | |
| SCHEMBL8546284 | 0.93 | NQO2 (0.39) | NQO2NQO1TOP2AMEN1USP2 | |
| SCHEMBL8541395 | 0.91 | NQO2 (0.38) | NQO2NQO1TOP2AMEN1USP2 | |
| SCHEMBL29369288 | 0.90 | IDO1 (0.37) | NQO2NQO1TOP2AIDO1MEN1 | |
| SCHEMBL105984 | 0.90 | IDO1 (0.37) | NQO2NQO1TOP2AIDO1MEN1 | |
| Hydrochloric Acid SCHEMBL1650422 | 0.89 | NQO2 (0.36) | NQO2NQO1TOP2AIDO1MEN1 | |
| SCHEMBL8547506 | 0.88 | NQO2 (0.36) | NQO2NQO1IDO1 | |
| SCHEMBL8545422 | 0.88 | NQO2 (0.42) | NQO2NQO1 | |
| SCHEMBL8543353 | 0.85 | NQO2 (0.37) | NQO2NQO1NSD2 | |
| SCHEMBL8548765 | 0.85 | NQO2 (0.36) | NQO2NQO1TOP2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487097-B1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5220026-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0487097-A1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |