Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8539619 | 0.99 | SLC6A2 (0.49) | SLC6A2BCHEMAPTKDM4EMEN1 | |
| SCHEMBL7611649 | 0.84 | SLC6A2 (0.65) | SLC6A2BCHE | |
| Hydrochloric Acid SCHEMBL3977692 | 0.83 | SLC6A2 (0.64) | SLC6A2BCHE | |
| SCHEMBL8441967 | 0.81 | SLC6A2 (0.73) | SLC6A2 | |
| SCHEMBL8544197 | 0.81 | BCHE (0.49) | SLC6A2BCHE | |
| SCHEMBL7621050 | 0.81 | BCHE (0.51) | SLC6A2BCHEMEN1KMT2A | |
| SCHEMBL8539188 | 0.81 | BCHE (0.55) | SLC6A2BCHEKDM4EMEN1GAA | |
| SCHEMBL7609605 | 0.81 | BCHE (0.68) | SLC6A2BCHE | |
| Hydrochloric Acid SCHEMBL8544417 | 0.80 | BCHE (0.51) | SLC6A2BCHEMEN1KMT2A | |
| SCHEMBL8539324 | 0.80 | BCHE (0.72) | SLC6A2BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5102891-A | Useful for treating various memory dysfunctions such as alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |