Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547696 | 0.93 | F2 (0.63) | F2ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8542963 | 0.91 | F2 (0.64) | F2ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8547585 | 0.90 | F2 (0.57) | F2ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8547659 | 0.90 | F2 (0.67) | F2ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8548737 | 0.89 | F2 (0.77) | F2ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8548163 | 0.88 | F2 (0.81) | F2ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8543114 | 0.84 | F2 (0.62) | F2ALDH1A1POLB | |
| SCHEMBL8542185 | 0.84 | F2 (0.58) | F2ATMMEN1KMT2A | |
| SCHEMBL8545469 | 0.83 | F2 (0.79) | F2ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8548135 | 0.83 | F2 (0.61) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |