⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783206 | 0.74 | — | — | |
| SCHEMBL10644479 | 0.70 | CYP1A2 (0.33) | — | |
| SCHEMBL8012453 | 0.69 | CMA1 (0.37) | — | |
| SCHEMBL11131208 | 0.68 | — | — | |
| SCHEMBL15346304 | 0.66 | — | — | |
| SCHEMBL28341880 | 0.66 | — | — | |
| SCHEMBL10784242 | 0.64 | — | — | |
| SCHEMBL29022844 | 0.64 | — | — | |
| SCHEMBL17185884 | 0.64 | — | — | |
| SCHEMBL14844714 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10233165-B2 | Cyclopropylamine compounds as histone demethylase inhibitors | ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2019-03-19 | — | — | US | disclosed |
| US-20170190680-A1 | CYCLOPROPYLAMINE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-07-06 | — | — | US | disclosed |
| EP-0817772-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1998-01-14 | — | — | EP | disclosed |