Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 6/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548935 | 1.00 | CYP2A6 (0.56) | CYP2A6MAPTMAPK1NPC1RAB9A | |
| SCHEMBL2803709 | 0.74 | CYP2A6 (0.53) | CYP2A6MAPTMAPK1NPC1RAB9A | |
| SCHEMBL2803711 | 0.74 | CYP2A6 (0.53) | CYP2A6MAPTMAPK1NPC1RAB9A | |
| SCHEMBL2803708 | 0.74 | CYP2A6 (0.53) | CYP2A6MAPTMAPK1NPC1RAB9A | |
| SCHEMBL8038555 | 0.74 | CYP2A6 (0.67) | CYP2A6MAPTMAPK1NPC1RAB9A | |
| SCHEMBL8038562 | 0.74 | CYP2A6 (0.67) | CYP2A6MAPTMAPK1NPC1RAB9A | |
| SCHEMBL25508775 | 0.73 | CYP2A6 (0.60) | CYP2A6MAPTMAPK1NPC1RAB9A | |
| SCHEMBL12884250 | 0.73 | APP (0.76) | CYP2A6MAPTMAPK1NPC1RAB9A | |
| SCHEMBL9956377 | 0.72 | CYP2A6 (1.00) | CYP2A6MAPTMAPK1NPC1RAB9A | |
| SCHEMBL29502957 | 0.72 | CYP2A6 (1.00) | CYP2A6MAPTMAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833630-A4 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN INC (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5763470-A | Benzopyran compounds and methods for their use | SUGEN INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0833630-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | Sugen, Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996040110-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |