Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270636 | 0.80 | MAPT (0.43) | MAPTBRPF1PRKCICDC7CDK2 | |
| SCHEMBL720541 | 0.78 | PRKCI (0.49) | MAPTBRPF1PRKCICDC7CDK2 | |
| SCHEMBL31735405 | 0.78 | PRKCI (0.49) | MAPTBRPF1PRKCICDC7CDK2 | |
| SCHEMBL30364924 | 0.77 | MAPT (0.48) | MAPTBRPF1PRKCICDC7CDK2 | |
| SCHEMBL2264468 | 0.77 | MAPT (0.48) | MAPTBRPF1PRKCICDC7CDK2 | |
| Hydrochloric Acid SCHEMBL6656724 | 0.76 | MAPT (0.47) | MAPTBRPF1PRKCICDC7CDK2 | |
| SCHEMBL31735741 | 0.76 | MAPT (0.57) | MAPTPRKCICDC7CDK2 | |
| Hydrochloric Acid SCHEMBL6654905 | 0.76 | MAPT (0.47) | MAPTBRPF1PRKCICDC7CDK2 | |
| SCHEMBL31735756 | 0.71 | PRKCI (0.49) | MAPTBRPF1PRKCICDC7CDK2 | |
| SCHEMBL29755944 | 0.71 | PRKCI (0.57) | MAPTBRPF1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405425-B1 | Heteroarylamino- and heteroaryloxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-08-12 | — | — | EP | claimed |