Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029955 | 0.81 | DPP4 (0.56) | PPARGPPARAFFAR1HPGDALDH1A1 | |
| SCHEMBL975049 | 0.81 | DPP4 (0.56) | PPARGPPARAFFAR1HPGDALDH1A1 | |
| SCHEMBL7299030 | 0.81 | CPA1 (0.61) | PPARGPPARAFFAR1HPGDALDH1A1 | |
| SCHEMBL975050 | 0.81 | DPP4 (0.56) | PPARGPPARAFFAR1HPGDALDH1A1 | |
| SCHEMBL11836998 | 0.81 | PPARG (0.48) | PPARGPPARAFFAR1HPGDALDH1A1 | |
| SCHEMBL29478407 | 0.81 | DPP4 (0.56) | PPARGPPARAFFAR1HPGDALDH1A1 | |
| SCHEMBL29478392 | 0.81 | DPP4 (0.56) | PPARGPPARAFFAR1HPGDALDH1A1 | |
| SCHEMBL4879473 | 0.79 | PPARG (0.43) | PPARGPPARAFFAR1HPGDALDH1A1 | |
| SCHEMBL4879468 | 0.79 | PPARG (0.43) | PPARGPPARAFFAR1HPGDALDH1A1 | |
| SCHEMBL4884341 | 0.79 | PPARG (0.43) | PPARGPPARAFFAR1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854863-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997003951-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |