Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594148 | 0.93 | EDNRB (0.79) | EDNRBEDNRA | |
| SCHEMBL8550472 | 0.91 | EDNRB (0.56) | EDNRBEDNRA | |
| SCHEMBL8550830 | 0.90 | EDNRB (0.70) | EDNRBEDNRA | |
| SCHEMBL8548004 | 0.88 | EDNRB (0.71) | EDNRBEDNRA | |
| SCHEMBL8547839 | 0.88 | EDNRB (0.52) | EDNRBEDNRA | |
| SCHEMBL8547921 | 0.86 | EDNRB (0.69) | EDNRBEDNRA | |
| SCHEMBL8551777 | 0.86 | EDNRB (0.65) | EDNRBEDNRA | |
| SCHEMBL8552414 | 0.85 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL8547603 | 0.83 | EDNRB (0.70) | EDNRBEDNRA | |
| SCHEMBL8594151 | 0.83 | EDNRB (0.63) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863898-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | MERCK PATENT GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997019077-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-05-29 | — | — | WO | disclosed |