Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4681919 | 0.98 | DHODH (0.34) | DHODHHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL4679808 | 0.81 | HTR2A (0.37) | HTR2AHTR2CHTR2BMAPTPOLB | |
| SCHEMBL10568715 | 0.81 | HTR2A (0.43) | HTR2AHTR2CMAPTPOLBNPSR1 | |
| SCHEMBL31442669 | 0.80 | CSNK2A1 (0.41) | DHODHLMNAMAPTALDH1A1POLB | |
| SCHEMBL4679825 | 0.80 | CSNK2A1 (0.41) | DHODHLMNAMAPTALDH1A1POLB | |
| SCHEMBL11211663 | 0.78 | DHODH (0.46) | DHODHLMNASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9834543 | 0.77 | DHODH (0.43) | DHODHLMNASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9775692 | 0.77 | DHODH (0.41) | DHODHLMNASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL6497939 | 0.76 | CYP11B1 (0.39) | DHODH | |
| SCHEMBL3228918 | 0.74 | CA1 (0.39) | NPC1NFKB1RAB9ANFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-01 | — | — | EP | disclosed |