Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.55 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551677 | 1.00 | TSHR (0.55) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL9726354 | 0.97 | TSHR (0.58) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL273087 | 0.97 | TSHR (0.58) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL6119157 | 0.89 | PPARA (0.50) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL17540753 | 0.89 | PPARA (0.50) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL17540740 | 0.89 | PPARA (0.50) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL17540746 | 0.89 | PPARA (0.50) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL28742746 | 0.89 | PPARA (0.50) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL30302045 | 0.88 | TSHR (0.50) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL12048807 | 0.87 | PPARA (0.64) | TSHRGABRR1GABRR2BLMGABRR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739358-A | Synthesis of acetogenins | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-04-14 | — | — | US | disclosed |
| US-5677467-A | Synthesis of acetogenins | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1997-10-14 | — | — | US | disclosed |