SCHEMBL8551695

SCHEMBL8551695

CN(c1ccc(Cn2oc(=O)[nH]c2=O)cc1)c1cccc(Oc2ccc(Cn3oc(=O)[nH]c3=O)cc2)c1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.44
PLAT P00750 4/20 0.41
KDM4C Q9H3R0 6/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MLNR O43193 1/20 0.35
DAO P14920 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8544251 0.86 FFAR1 (0.48) FFAR1PLATMEN1KMT2ADAO
SCHEMBL8550218 0.83 FFAR1 (0.40) FFAR1PLATMEN1KMT2ADAO
SCHEMBL8549634 0.83 FFAR1 (0.43) FFAR1PLATMEN1KMT2ADAO
SCHEMBL12580011 0.82 FFAR1 (0.57) FFAR1PLAT
SCHEMBL8546551 0.81 FFAR1 (0.46) FFAR1PLATMEN1KMT2ADAO
SCHEMBL8550945 0.81 FFAR1 (0.46) FFAR1PLATMEN1KMT2ADAO
SCHEMBL8953815 0.78 PLAT (0.53) FFAR1PLAT
SCHEMBL8550204 0.78 PLAT (0.43) FFAR1PLATMEN1KMT2ADAO
SCHEMBL12578551 0.77 FFAR1 (0.58) FFAR1PLATMEN1KMT2ADAO
SCHEMBL12578796 0.77 FFAR1 (0.58) FFAR1PLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696585-B1 NOVEL BISOXADIAZOLIDINE DERIVATIVE YAMANOUCHI PHARMA CO LTD (JP) 1998-12-16 EP disclosed
US-5643931-A ANTIDIABETIC AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1997-07-01 US disclosed
EP-0696585-A1 NOVEL BISOXADIAZOLIDINE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-02-14 EP disclosed