Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | CBS | P35520 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 3/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182447 | 0.82 | TSHR (0.47) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL10495649 | 0.79 | TSHR (0.45) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL27512674 | 0.79 | SOAT1 (0.40) | TSHRSOAT1FFAR3 | |
| SCHEMBL5270527 | 0.77 | SOAT1 (0.41) | SOAT1FFAR3 | |
| SCHEMBL3057906 | 0.76 | — | — | |
| SCHEMBL30288115 | 0.73 | — | — | |
| SCHEMBL29951822 | 0.72 | — | — | |
| SCHEMBL510170 | 0.72 | — | — | |
| SCHEMBL254444 | 0.71 | CA1 (0.33) | TSHRSOAT1FFAR3 | |
| SCHEMBL21611838 | 0.70 | TSHR (0.38) | TSHRCTHCBSTHPOTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721950-B1 | Cardioactive 3-alkoxycarbonyl-thiadiazinones | MERCK PATENT GMBH (DE) | 1998-05-06 | — | — | EP | disclosed |
| EP-0721950-A2 | Cardioactive 3-alkoxycarbonyl-thiadiazinones | MERCK PATENT GmbH (DE) | 1996-07-17 | — | — | EP | disclosed |