Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12562393 | 0.82 | KCNN4 (0.36) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27130312 | 0.76 | MEN1 (0.38) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1114389 | 0.75 | KMT2A (0.40) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL210129 | 0.71 | CA4 (0.41) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18651744 | 0.70 | MEN1 (0.32) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4893317 | 0.70 | KCNN4 (0.42) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4894696 | 0.70 | KCNN4 (0.42) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9507537 | 0.70 | MEN1 (0.39) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL21273293 | 0.69 | CA4 (0.39) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27595853 | 0.69 | CA4 (0.39) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780245-A | SEROTONIN AGONISTS AND ANTAGONISTS; TREATMENT OF CARDIOVASCULAR DISORDERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-07-14 | — | — | US | disclosed |
| EP-0665885-A1 | POLYPEPTIDES (5HT2C) HAVING A SEROTONINERGIC RECEPTOR ACTIVITY AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994009130-A1 | POLYPEPTIDES (5HT2C) HAVING A SEROTONINERGIC RECEPTOR ACTIVITY AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-04-28 | — | — | WO | disclosed |