SCHEMBL855211

SCHEMBL855211

COCCNc1cc(N)ccc1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 4/20 0.51
ALDH1A1 P00352 4/20 0.49
MAPT P10636 4/20 0.49
NCF1 P14598 2/20 0.47
LMNA P02545 1/20 0.42
NQO2 P16083 3/20 0.38
HCAR3 P49019 1/20 0.38
KDM4E B2RXH2 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 2/20 0.36
MAPK1 P28482 1/20 0.36
UTS2R Q9UKP6 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
CASP1 P29466 1/20 0.35
HTT P42858 1/20 0.35
CASP7 P55210 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14616763 0.84 PTGER4 (0.50) PTGER4ALDH1A1MAPTNCF1LMNA
SCHEMBL13015196 0.84 PTGER4 (0.47) PTGER4ALDH1A1MAPTNCF1LMNA
SCHEMBL6574666 0.83 PTGER4 (0.50) PTGER4ALDH1A1MAPTNCF1LMNA
SCHEMBL17845272 0.83 PTGER4 (0.49) PTGER4ALDH1A1MAPTNCF1LMNA
SCHEMBL31122067 0.83 PTGER4 (0.49) PTGER4ALDH1A1MAPTNCF1LMNA
SCHEMBL1519220 0.83 PTGER4 (0.49) PTGER4ALDH1A1MAPTNCF1LMNA
SCHEMBL16407615 0.83 PTGER4 (0.49) PTGER4ALDH1A1MAPTNCF1LMNA
SCHEMBL9499759 0.81 PTGER4 (0.50) PTGER4ALDH1A1MAPTNCF1LMNA
SCHEMBL11311817 0.81 PTGER4 (0.50) PTGER4ALDH1A1MAPTNCF1LMNA
SCHEMBL9499986 0.79 PTGER4 (0.49) PTGER4ALDH1A1MAPTNCF1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1473025-B1 Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer OREAL (FR) 2012-03-28 EP claimed
EP-1410788-B1 Oxidation dyeing composition for keratinous fibres comprising 2-chloro 6 methyl 3-aminophenol, an oxidation base and an additional coupler, and dyeing method OREAL (FR) 2006-05-10 EP claimed
EP-0966251-B1 OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES COMPRISING 2-CHLORO 6-METHYL 3-AMINOPHENOL AND TWO OXIDATION BASES, AND DYEING METHOD OREAL (FR) 2005-12-14 EP claimed
EP-1493426-A1 Dyeing composition comprising a developer, 2-chloro-6-methyl-3-aminophenol and 3-methyl-5-pyrazolone L'OREAL (FR) 2005-01-05 EP claimed
EP-0966250-B1 OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES COMPRISING 2-CHLORO 6 METHYL 3-AMINOPHENOL, AN OXIDATION BASE AND AN ADDITIONAL COUPLER, AND DYEING METHOD OREAL (FR) 2004-11-17 EP claimed
EP-1473025-A1 Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer L'OREAL (FR) 2004-11-03 EP claimed
US-6379396-B1 HAIR DYES WITH PHENYLENEDIAMINES AND AMINOPHENOLS L'ORéAL S.A. (FR) 2002-04-30 US claimed
US-6306180-B1 FOR COLORING HUMAN HAIR; RESISTANCE TO LIGHT AND BAD WEATHER, AND WITH RESPECT TO PERSPIRATION, SHAMPOOING ETC. L'OREAL, S.A. (FR) 2001-10-23 US claimed
US-6277156-B1 OXIDATION BASE ARE PARAPHENYLENEDIAMINES, DOUBLE BASES; PYRAZOLO(1,5-A)PYRIMIDINES ORTHO-AMINOPHENOLS; DIAMINOPYRIDINES L'ORéAL S.A. (FR) 2001-08-21 US claimed
US-6379396-B1 HAIR DYES WITH PHENYLENEDIAMINES AND AMINOPHENOLS L'ORéAL S.A. (FR) 2002-04-30 US disclosed
US-6306180-B1 FOR COLORING HUMAN HAIR; RESISTANCE TO LIGHT AND BAD WEATHER, AND WITH RESPECT TO PERSPIRATION, SHAMPOOING ETC. L'OREAL, S.A. (FR) 2001-10-23 US disclosed
US-6277156-B1 OXIDATION BASE ARE PARAPHENYLENEDIAMINES, DOUBLE BASES; PYRAZOLO(1,5-A)PYRIMIDINES ORTHO-AMINOPHENOLS; DIAMINOPYRIDINES L'ORéAL S.A. (FR) 2001-08-21 US disclosed