Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 8/20 | 0.45 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710270 | 0.91 | CYP3A4 (0.49) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11140235 | 0.90 | S1PR3 (0.59) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11141588 | 0.90 | S1PR3 (0.59) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11139070 | 0.90 | S1PR3 (0.59) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11146052 | 0.90 | S1PR3 (0.59) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11140057 | 0.90 | S1PR3 (0.59) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11134778 | 0.90 | S1PR3 (0.59) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11140464 | 0.90 | S1PR3 (0.59) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11144184 | 0.90 | S1PR3 (0.59) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11141188 | 0.90 | S1PR3 (0.59) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |