Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | PPARD | Q03181 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metaxon SCHEMBL8386962 | 0.95 | TDP1 (0.59) | TDP1TSHRPPARDCYP2C19NPSR1 | |
| Metaxon SCHEMBL9718318 | 0.92 | TDP1 (0.82) | TDP1TSHRPPARDCYP2C19NPSR1 | |
| Metaxon SCHEMBL11008133 | 0.87 | TDP1 (0.53) | TDP1TSHRPPARDCYP2C19NPSR1 | |
| Metaxon SCHEMBL117877 | 0.86 | TDP1 (0.70) | TDP1TSHRPPARDNPSR1PPARG | |
| Metaxon SCHEMBL27765431 | 0.85 | TDP1 (0.68) | TDP1TSHRPPARDNPSR1PPARG | |
| Metaxon SCHEMBL27616565 | 0.85 | TDP1 (0.68) | TDP1TSHRPPARDNPSR1PPARG | |
| Metaxon SCHEMBL18221951 | 0.85 | TDP1 (0.68) | TDP1TSHRPPARDNPSR1PPARG | |
| Metaxon SCHEMBL3533162 | 0.85 | TDP1 (0.68) | TDP1TSHRPPARDNPSR1PPARG | |
| Metaxon SCHEMBL28800416 | 0.85 | TDP1 (0.68) | TDP1TSHRPPARDNPSR1PPARG | |
| Mcpb SCHEMBL9445864 | 0.85 | TDP1 (0.69) | TDP1TSHRPPARDCYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846105-A1 | HERBICIDAL SUBSTITUTED 3-ARYL-PYRAZOLES | MONSANTO COMPANY (US) | 1998-06-10 | — | — | EP | disclosed |