SCHEMBL8553288

SCHEMBL8553288

Cc1ccc(CCCC2CCCNC2)c2nc(COc3ccc(Cl)cc3)[nH]c12

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 19/20 0.53
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8554556 0.86 NPY1R (0.51) NPY1R
SCHEMBL8555992 0.85 NPY1R (0.51) NPY1R
SCHEMBL8551656 0.83 NPY1R (0.50) NPY1R
SCHEMBL8550720 0.82 NPY1R (0.53) NPY1R
SCHEMBL8551284 0.82 NPY1R (0.50) NPY1R
SCHEMBL8554871 0.82 NPY1R (0.50) NPY1R
SCHEMBL8553363 0.81 NPY1R (0.48) NPY1R
SCHEMBL8554219 0.80 NPY1R (0.51) NPY1R
SCHEMBL8553094 0.79 NPY1R (0.50) NPY1R
SCHEMBL8554085 0.79 NPY1R (0.49) NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0871442-A1 BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1998-10-21 EP disclosed
WO-1997025041-A1 BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1997-07-17 WO disclosed