SCHEMBL8553982

SCHEMBL8553982

C1=Cc2ccc3occc3c2OC1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2B6 P20813 1/20 0.37
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
FTO Q9C0B1 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29657636 1.00 CYP1A1 (0.40) CYP1A1CYP1A2CYP2B6HTR2AHTR2C
SCHEMBL6629828 0.75 CYP1A2 (0.47) CYP1A1CYP1A2CYP2B6MAOAMAOB
SCHEMBL9101318 0.71 CYP1A2 (0.40) CYP1A1CYP1A2CYP2B6HTR2AHTR2C
SCHEMBL9099368 0.71 CYP1A1 (0.38) CYP1A1CYP1A2CYP2B6HTR2AHTR2C
SCHEMBL29474440 0.70 HTR2A (0.42) HTR2AHTR2CHTR2BMAOAMAOB
SCHEMBL1043402 0.69 CYP2B6 (0.43) CYP1A1CYP1A2CYP2B6HTR2B
SCHEMBL29372595 0.69 CYP2B6 (0.43) CYP1A1CYP1A2CYP2B6HTR2B
SCHEMBL29365059 0.69 CYP2B6 (0.43) CYP1A1CYP1A2CYP2B6HTR2B
SCHEMBL2186959 0.69 CYP1A1 (0.55) CYP1A1CYP1A2CYP2B6MAOA
SCHEMBL6714839 0.68 HTR2A (0.33) HTR2AHTR2CHTR2BMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0572001-B1 Furobenzopyran derivatives, process for preparation of same and herbicides containing same as active components MITSUI CHEMICALS INC (JP) 1998-08-05 EP claimed
US-5356866-A Completely selective to crops such as paddy rice, soybeans and cotton MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-18 US claimed
EP-0572001-A1 Furobenzopyran derivatives, process for preparation of same and herbicides containing same as active components MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-12-01 EP claimed
JP-7138110-A None JP disclosed
JP-7145009-A None JP disclosed
JP-7145007-A None JP disclosed
JP-7145008-A None JP disclosed
JP-8268814-A None JP disclosed
JP-8268812-A None JP disclosed
JP-8268813-A None JP disclosed
JP-8268815-A None JP disclosed
JP-H07138111-A HERBICIDE COMPOSITION FOR PADDY FIELD MITSUI TOATSU CHEM INC 1995-05-30 JP disclosed
US-5356866-A Completely selective to crops such as paddy rice, soybeans and cotton MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-18 US disclosed
US-5356866-A Completely selective to crops such as paddy rice, soybeans and cotton MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-18 US disclosed
US-5356866-A Completely selective to crops such as paddy rice, soybeans and cotton MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-18 US disclosed
EP-0572001-A1 Furobenzopyran derivatives, process for preparation of same and herbicides containing same as active components MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-12-01 EP disclosed
EP-0572001-A1 Furobenzopyran derivatives, process for preparation of same and herbicides containing same as active components MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-12-01 EP disclosed
EP-0572001-A1 Furobenzopyran derivatives, process for preparation of same and herbicides containing same as active components MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-12-01 EP disclosed
EP-0094768-B1 FUROCHROMONES AND FUROBENZOPYRANS THE UPJOHN COMPANY (US) 1986-11-26 EP disclosed
EP-0094768-A1 Furochromones and furobenzopyrans THE UPJOHN COMPANY (US) 1983-11-23 EP disclosed