Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | WDR5 | P61964 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503506 | 0.95 | CYP2C9 (0.60) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9026559 | 0.91 | CYP2C9 (0.59) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8503277 | 0.91 | CYP2C9 (0.61) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3911587 | 0.90 | CYP1A2 (0.63) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10335251 | 0.89 | CYP1A2 (0.64) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9025979 | 0.88 | CYP2C9 (0.56) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8130091 | 0.86 | CYP1A2 (0.60) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8552373 | 0.85 | CYP2D6 (0.54) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10965135 | 0.85 | CYP2D6 (0.65) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8502428 | 0.84 | CYP2C9 (0.54) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0295603-B1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | EISAI CO LTD (JP) | 1996-09-18 | — | — | EP | disclosed |
| EP-0295603-A1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | Eisai Co., Ltd. (JP) | 1988-12-21 | — | — | EP | disclosed |