Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 18/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553094 | 0.93 | NPY1R (0.50) | NPY1RACP1 | |
| Trifluoroacetic Acid SCHEMBL8552866 | 0.92 | NPY1R (0.48) | NPY1RHRH4 | |
| Trifluoroacetic Acid SCHEMBL8552498 | 0.87 | NPY1R (0.44) | NPY1R | |
| Trifluoroacetic Acid SCHEMBL8552860 | 0.85 | NPY1R (0.48) | NPY1R | |
| Trifluoroacetic Acid SCHEMBL8555689 | 0.85 | NPY1R (0.45) | NPY1RHRH4 | |
| Trifluoroacetic Acid SCHEMBL8555314 | 0.85 | NPY1R (0.45) | NPY1RHRH4 | |
| SCHEMBL8554219 | 0.83 | NPY1R (0.51) | NPY1R | |
| SCHEMBL8553471 | 0.81 | NPY1R (0.46) | NPY1R | |
| Trifluoroacetic Acid SCHEMBL8552526 | 0.80 | NPY1R (0.41) | NPY1R | |
| SCHEMBL8554556 | 0.80 | NPY1R (0.51) | NPY1RHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |