Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889632 | 0.75 | — | — | |
| SCHEMBL21845576 | 0.68 | PDE7A (0.33) | ALDH1A1PKMGAA | |
| SCHEMBL21845476 | 0.66 | TSHR (0.32) | MAPTHPGDTSHRTAAR1HSD17B10 | |
| SCHEMBL6733149 | 0.61 | — | — | |
| SCHEMBL26607001 | 0.61 | — | — | |
| SCHEMBL30888670 | 0.60 | MAPT (0.34) | MAPTHPGDTSHRTAAR1HSD17B10 | |
| SCHEMBL6721324 | 0.59 | — | — | |
| SCHEMBL30643117 | 0.59 | BACE1 (0.44) | HPGDLMNA | |
| SCHEMBL14053247 | 0.58 | BACE1 (0.38) | — | |
| SCHEMBL30100082 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885936-A | BENZOTHIOPYRAN DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0860441-A1 | Herbicidal derivatives of 1,4-dithiino(2,3c)benzothiopyran | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-26 | — | — | EP | disclosed |