Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15209940 | 0.81 | MALT1 (0.47) | KMT2AKDM4EMEN1MALT1SLC9A1 | |
| SCHEMBL1457164 | 0.79 | KMT2A (0.51) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL1456670 | 0.79 | KMT2A (0.59) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL1457376 | 0.79 | KMT2A (0.57) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL839068 | 0.79 | KMT2A (0.51) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL1456326 | 0.77 | KMT2A (0.58) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL838856 | 0.77 | KMT2A (0.51) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL8041487 | 0.77 | KMT2A (0.56) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL1456603 | 0.77 | KMT2A (0.51) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL14477402 | 0.75 | KMT2A (0.48) | KMT2AKDM4EMEN1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |