Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 8/20 | 0.40 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554909 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C8S1PR3CYP2C9CYP2D6 | |
| SCHEMBL11196945 | 0.86 | SPHK1 (0.50) | CYP2C9SPHK1GAAMAPTSPHK2 | |
| SCHEMBL11196951 | 0.86 | SPHK1 (0.50) | CYP2C9SPHK1GAAMAPTSPHK2 | |
| SCHEMBL11188896 | 0.86 | SPHK1 (0.50) | CYP2C9SPHK1GAAMAPTSPHK2 | |
| SCHEMBL11191523 | 0.86 | SPHK1 (0.50) | CYP2C9SPHK1GAAMAPTSPHK2 | |
| SCHEMBL11191518 | 0.86 | SPHK1 (0.50) | CYP2C9SPHK1GAAMAPTSPHK2 | |
| SCHEMBL11198137 | 0.86 | SPHK1 (0.50) | CYP2C9SPHK1GAAMAPTSPHK2 | |
| SCHEMBL11190738 | 0.86 | SPHK1 (0.50) | CYP2C9SPHK1GAAMAPTSPHK2 | |
| SCHEMBL11190177 | 0.86 | SPHK1 (0.50) | CYP2C9SPHK1GAAMAPTSPHK2 | |
| SCHEMBL11241897 | 0.86 | SPHK1 (0.50) | CYP2C9SPHK1GAAMAPTSPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |