Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045822 | 0.98 | TAAR1 (0.55) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL9305800 | 0.98 | TAAR1 (0.55) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL1044622 | 0.94 | TAAR1 (0.59) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL19524669 | 0.87 | TAAR1 (0.65) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL1007645 | 0.85 | TAAR1 (0.63) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL5240585 | 0.85 | TAAR1 (0.68) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL13569139 | 0.83 | TAAR1 (0.61) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL28585404 | 0.82 | TAAR1 (0.59) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL16203114 | 0.82 | TAAR1 (0.59) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL30444743 | 0.82 | TAAR1 (0.59) | TAAR1IDO1AGXTMAOBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |