Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556223 | 0.94 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL27657033 | 0.92 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 | |
| SCHEMBL8557616 | 0.88 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 | |
| SCHEMBL8559522 | 0.87 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 | |
| SCHEMBL8554465 | 0.86 | TDP1 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 | |
| SCHEMBL8552812 | 0.86 | TDP1 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 | |
| SCHEMBL8553944 | 0.86 | TDP1 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 | |
| SCHEMBL8559635 | 0.86 | TDP1 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 | |
| SCHEMBL8558958 | 0.86 | TDP1 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 | |
| SCHEMBL8556087 | 0.86 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |