Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556232 | 0.89 | SSTR4 (0.37) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL8555647 | 0.80 | KDM4E (0.36) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL8558961 | 0.79 | SLC6A2 (0.32) | SLC6A2SLC6A4KDM4EALDH1A1SLC6A3 | |
| SCHEMBL28107993 | 0.77 | PARP1 (0.40) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL8557624 | 0.76 | SLC6A2 (0.34) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL8559529 | 0.75 | SLC6A2 (0.34) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL8554467 | 0.74 | SLC6A2 (0.33) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL8552813 | 0.74 | SLC6A2 (0.33) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL8553945 | 0.74 | SLC6A2 (0.33) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL8559643 | 0.74 | SLC6A2 (0.33) | SLC6A2SLC6A4KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |