⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360801 | 0.88 | F2 (0.35) | — | |
| SCHEMBL6362494 | 0.80 | — | — | |
| SCHEMBL442261 | 0.78 | — | — | |
| SCHEMBL28547061 | 0.77 | — | — | |
| SCHEMBL64615 | 0.75 | — | — | |
| SCHEMBL12187922 | 0.75 | F2 (0.46) | — | |
| SCHEMBL12208456 | 0.75 | PIK3CD (0.38) | — | |
| SCHEMBL5004378 | 0.75 | F2 (0.33) | — | |
| SCHEMBL16349791 | 0.75 | TOP2A (0.52) | — | |
| SCHEMBL13798772 | 0.75 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156323-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-08-06 | — | — | WO | disclosed |
| EP-3012258-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AND -TRIAZINES AS ANTIVIRAL AGENTS | Gilead Sciences, Inc. (US) | 2016-04-27 | — | — | EP | disclosed |
| US-20090227792-A1 | HIGHLY REACTIVE a-AMINOMETHYL-ALKOXYSILANES HAVING IMPROVED STABILITY | WACKER CHEMIE AG (DE) | 2009-09-10 | — | — | US | disclosed |
| EP-0858451-A1 | PHARMACEUTICALLY ACTIVE QUINAZOLINE COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997014686-A1 | PHARMACEUTICALLY ACTIVE QUINAZOLINE COMPOUNDS | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-04-24 | — | — | WO | disclosed |